Jc uppsala. Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial 2020-01-01

Safety Monitoring of Medicinal Products: Guidelines for Setting Up and Running a Pharmacovigilance Centre: CAUSALITY CATEGORIES

Similar but attenuated associations were observed when palmitate uptake was assessed as net uptake rate K i. Microarrays: Use in Mutation Detection. PhD theses Dahlberg, Johan 2018 Faculty opponent: Dr Michael C. Sætre G-P, Borge T, Lindroos K, Haavie J, Sheldon B C , Primmer C, Syvänen A-C. Clinical and laboratory analyses Participants completed an oral glucose tolerance test by consuming 75 g glucose dissolved in 200 mL water blood sampling at 0, 30, 60, and 120 minutes.

Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial

Total body and visceral fat were quantified using a previously described automated image analysis algorithm. Information on drug withdrawal may be lacking or unclear. Pastinen T, Perola M, Ignatius J, Sabatti C, Tainola P, Levander M, Syvänen A-C and Peltonen L. An increased intake of palmitate is expected to play a key role in the ceramide synthesis rate generated by the de novo synthesis pathway, but mechanistic data are lacking in humans. Miscellaneous Syvänen A-C Connecting genomics and clinical research. Clinical Laboratory International 2002, 26, 6-9.

Category:Uppsala

Relative change from baseline % in serum. During this 4-day periods, subjects wore accelerometers Philips Respironics Actical on their right ankle to assess 24-hour physical activity. The absolute amount of liver fat in liters was calculated by the multiplication of liver volume by liver fat content %. Accessing genetic variation: Genotyping single nucleotide polymorphisms. Thus, both key dietary biomarkers, as well as self-reported data, suggested excellent compliance to both diets. The role of causality assessment in pharmacovigilance.

Safety Monitoring of Medicinal Products: Guidelines for Setting Up and Running a Pharmacovigilance Centre: CAUSALITY CATEGORIES

Potential effects of dietary fat type on other ectopic fat depots of potential clinical relevance, such as pancreas fat, are unknown. Certain: a clinical event, including laboratory test abnormality, occurring in a plausible time relationship to drug administration, and which cannot be explained by concurrent disease or other drugs or chemicals. Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation. Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus. In both groups combined, none of the measurements changed as a result of the intervention data not shown. Possible: a clinical event, including laboratory test abnormality, with a reasonable time sequence to administrations of the drug, but which could also be explained by concurrent disease or other drugs or chemicals.

Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia - A comparative study of four differently designed, high resolution microarray platforms. Liver and pancreas fat Liver fat increased by 53% 1. Double-blinding was ensured by labeling, and the code was concealed from all investigators until study completion and statistical analyses of primary outcomes. A, Luikart G, Wayne R. Lovmar L, Fock C, Espinoza F, Bucardo F, Syvänen A-C, Bondeson K.

JC Jeans & Clothes (Now Closed)

Syvänen A-C, Nilbert M, Björkegren J. Additional Information Disclosure Summary: The authors have nothing to disclose. Body weight was measured, and muffins were provided to subjects weekly at the clinic. In both groups combined, changes in ceramides and sphingolipids showed diverse effects in response to weight loss. SweGen: A whole-genome map of genetic variability in a cross-section of the Swedish population. Change in liver fat in this subgroup reflected that seen in the full sample.

Simon Monserrat

Only one subject dropped out, thus minimizing attrition bias. Patent families Söderlund H, Syvänen A-C: Method for determining specific nucleotide variations. Dietary fat-specific effects on circulating ceramides have recently been suggested in humans. All authors reviewed and approved the final manuscript. For the exploratory assessment of hepatic palmitate uptake, we had no previous data to use for sample-size determination.

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells. Silander K, Axelsson T, Widén E, Dahlgren A, Palotie A, Syvänen A-C. The strong agreement between this study and our previous data , , provides validity and reproducibility of these results. Clincal Laboratory International 2002, 26: 6-9. Dissociation between hepatic fatty acid uptake and liver fat content was recently observed by Immonen et al. Sara Wedrén, Lovisa Lovmar, Keith Humphreys, Cecilia Magnusson, Håkan Melhus, Ann-Christine Syvänen, Andreas Kindmark, Ulf Landegren, Maria Lagerström Fermér, Fredrik Stiger, Ingemar Persson, John Baron, Elisabete Weiderpass.

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

Except for fat type, muffins were identical in composition 51 energy% fat, 44 energy% carbohydrates, and 5 energy% protein. Milani L, Fredriksson M, Syvänen A-C. Lagerstrom-Fermer M, Larhammar D, Johnsen E, Landegren U. Liljedahl U, Lind L, Kurland L, Berglund L, Kahan T, Syvänen A-C. Liljedahl U, Fredriksson M, Dahlgren A, Syvänen A-C. In addition, ceramide species in plasma correlate with the respective species in human livers.